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    Prostate Cancer 24m 10s

    Case based Learning: Whole genome sequencing in Prostate Cancer

    Published 11 Jul 2022
    Dr. Enrique Grande describes case scenario of patient with prostate cancer with high volume
    high grade tumor (Gleason 9, 4+5)

    Patient was initially treated with ADT + Abiraterone + Prednisone followed by treatment
    with docetaxel. On further progression was offered molecular testing and was treated with
    targeted agent, PARP inhibitor.

    Following aspects of case are covered:
    • Role of whole genome sequencing and precision medicine in the field of castration resistant prostate cancer (CRPC)
    • PAPR inhibitors for the treatment of patients with BRCA 1/2 alteration after progression on androgen receptor targeting agents
    • Liquid biopsy to overcome challenges of tissue analysis
    precision medicine prostate cancer whole genome sequencing

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