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Breast Cancer36m 42s
Clinical Challenges in Management of Hormone Receptor Positive -Her 2 Negative Advanced Breast Cancer (ABC)
The landscape of HR+ve/HER2-negative metastatic breast cancer (MBC) has evolved significantly with the introduction of newer treatment options such as CDK4/6 inhibitors, PI3K inhibitors, and selective estrogen receptor down regulators.
management of hr+/her2- breast cancer
cdk4/6 inhibitors
serds
pi3k inhibitors
biomarkers
1
Clinical Challenges in Management of Hormone...
Prostate Cancer6m 59s
Managing Nonmetastatic Castration-Resistant Prostate Cancer (nmCRPC)
3 randomized clinical trials (SPRATAN- Apalutamide), (PROSPER -Enzalutamide) & (ARAMIS -Darolutamide) have shown consistent and almost similar benefit in Metastasis Free Survival in nmCRPC
nmcrpc
metastasis free survival
spartan
prosper & aramis clinical trial
1
Managing Nonmetastatic Castration-Resistant...
Multiple Myeloma10m 40s
Recommendations -Management of Myeloma Related Renal Impairment
Supportive Care, Mechanical Approach and Systemic Antimyeloma treatment are 3 pillars of management of Myeloma related renal impairment. In supportive care prompt initiation of high fluid administration, appropriate use of Bisphosphonates can help.
myeloma
renal impairment
lancet guidelines
1
Recommendations -Management of Myeloma Related...
Breast Cancer3m 56s
Duration of trastuzumab in patients with Her2 positive Metastatic Breast Cancer in prolonged remission
There are no randomized clinical trials addressing the continued use of Trastuzumab for Her2 positive MBC patients in prolonged remission and has become important and relevant clinical question.
her2 positive mbc
prolonged remission
trastuzumab duration
1
Duration of trastuzumab in patients with Her2...
Multiple Myeloma9m 20s
Integrating Pomalidomide Based Regimens in Multiple Myeloma
Integrating pomalidomide and dexamethasone in the treatment of relapsed or refractory multiple myeloma (RRMM) involves using them as a core regimen, often combined with other agents like bortezomib or monoclonal antibodies for enhanced efficacy.
pomalidomide-dexamethasone
rrmm management
progression-free survival
combination therapies
1
Integrating Pomalidomide Based Regimens in Multiple...
Myelodysplastic Syndromes8m 45s
Current Challenges in MDS Diagnosis and Consequences
Bone marrow examination-based diagnosis of MDS with either biopsy or aspirate remains standard of care but is associated with pain, bleeding, difficulty to use the same in elderly patients and hIgh interobserver variability.
non invasive mds diagnosis
web based mds diagnosis tools
1
Current Challenges in MDS Diagnosis and Consequences
Myelodysplastic Syndromes5m 42s
Integrating Molecular Prognositic Systems in Management of MDS
Integrating molecular prognostic systems into MDS clinical practice enhances risk stratification by combining genetic data with traditional scoring systems.
molecular prognostic systems
ipss-m
prediction of disease progression
1
Integrating Molecular Prognositic Systems in...
Prostate Cancer11m 38s
Treatment Intensification in Metastatic Castration Sensitive Prostate Cancer
PEACE-1 clinical trial demonstrated that combining ADT and docetaxel with abiraterone acetate plus prednisone (AAP) improves both overall survival (OS) and radiographic progression-free-survival (rPFS) in men with de novo mCSPC.
treatment intensification
mhspc
triplet therapy
peace-1 clinical trial
1
Treatment Intensification in Metastatic Castration...
Multiple Myeloma7m 42s
MRD Assesment in Multiple Myeloma -Ready for Prime Time
Multiple Myeloma is an incurable disease with patients relapsing even after achieving deep responses. Minimal Residual Disease (MRD) represents a relatively new way of evaluating response to treatment.
minimum residual disease (mrd)
mrd negativity
multiple myeloma
1
MRD Assesment in Multiple Myeloma -Ready for Prime...
Myelodysplastic Syndromes7m 3s
Clinical Application of Web Based Tool for Improving MDS Diagnosis
Gradient Based Model based on 10 routinely used parameters (Age, Gender, Hb, WBC, MCV, Platelets, Neutrophils, Monocytes, Glucose, Creatinine) is now available to facilitate non-invasive diagnosis of MDS.
mds
non-invasive diagnosis
1
Clinical Application of Web Based Tool for...
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